The invention discloses a real-time communication method and equipment used among multiple main station systems. The real-time communication equipment is connected into two sets of independent main station systems in series and comprises two auxiliary stations and a real-time communication controller. Main stations and the auxiliary stations communicate in real time according to a real-time communication protocol. The auxiliary stations communicate in real time under coordination of the real-time communication controller. The real-time communication controller controls the auxiliary stations to carry out real-time data transmission through a real-time data buffer by monitoring the working states of the auxiliary stations. According to the method and the equipment, real-time communication between the two main stations is converted into real-time communication between the auxiliary stations of the two main station systems, bi-directional real-time communication between the independent main station systems can be achieved, and the real-time communication requirement of application occasions with the high speed and the high reliability can be met.