利索-全球专利检索

  1. 登录
  2. 注册
发明公开
CN104031143A 一种抗鲤科疱疹病毒3型鸡卵黄抗体及其制备方法和应用 无效 - 驳回

一种抗鲤科疱疹病毒3型鸡卵黄抗体及其制备方法和应用
摘要：
本发明公开了一种抗鲤科疱疹病毒3型鸡卵黄抗体的制备方法，以鲤科疱疹病毒3型作为抗原，免疫蛋鸡，测定卵黄抗体效价后，收集免疫卵，分离卵黄，纯化后获得抗鲤科疱疹病毒3型鸡卵黄抗体。还公开了由上述方法制成的抗鲤科疱疹病毒3型鸡卵黄抗体及该卵黄抗体在制备检测、预防或治疗鲤科疱疹病毒3型感染引起的相关疾病的药物中的应用及在制备预防和/或治疗鲤科疱疹病毒3型感染引起的相关疾病的饲料添加剂中的应用；本发明方法采用差速离心方法纯化的鲤科疱疹病毒3型具有较高的回收率和较好的囊膜完整性，适于大规模纯化病毒；本发明制备的抗鲤科疱疹病毒3型鸡卵黄抗体纯度高，易于产业化，可显著降低鲤科疱疹病毒3型感染造成的锦鲤死亡率。
摘要（英）：

The invention discloses a preparation method of a cyprinidae herpes virusIII-resisting chicken egg-yolk antibody. The method is characterized in that the cyprinidae herpes virus III is used as an antigen to immunize a chicken egg; after the titer of the chicken egg-yolk antibody is determined, the immunized egg is collected, the egg yolk is separated, and the egg yolk is purified to obtain the cyprinidae herpes virusIII-resisting chicken egg-yolk antibody. The invention also discloses a cyprinidae herpes virusIII-resisting chicken egg-yolk antibody prepared through the method, an application of the cyprinidae herpes virusIII-resisting chicken egg-yolk antibody in preparation of drugs for detecting, preventing or treating relevant diseases caused by infecting the cyprinidae herpes virus III and an application of the cyprinidae herpes virus-resisting type-III chicken egg-yolk antibody in preparation of feed additive for preventing and/or treating relevant diseases caused by infecting the cyprinidae herpes virus. The cyprinidae herpes virusIII-resistinng chicken egg-yolk antibody prepared through the method is high in purity, easy to industrialize and capable of remarkably reducing the dead rate of koi caused by the infection of the cyprinidae herpes virus III.

0/0