The invention discloses a driving method of a color sequence type liquid crystal display. The driving method comprises the steps that four pixel grayscale values of each frame are calculated, and include the white pixel grayscale value, the first-color pixel grayscale value, the second-color pixel grayscale value and the third-color pixel grayscale value; in a first color field of the n frame, a white backlight source is provided for a pixel unit, the white pixel grayscale value of the n frame is input into a transparent sub-pixel, the first-color pixel grayscale value of the n frame is input into a first-color sub-pixel, and the second-color pixel grayscale value of the n frame is input into a second-color sub-pixel; in a second color field of the n frame, a third-color backlight source is provided for a pixel unit, the third-color pixel grayscale value of the n frame is input into a transparent sub-pixel, two grayscale values are input into a first-color sub-pixel and a second-color sub-pixel respectively, and the first-color sub-pixel and the second-color sub-pixel are kept in the on state. The invention further discloses the color sequence type liquid crystal display which is driven by adopting the driving method.