The invention discloses a catheter with an atherosclerotic plaque cutting and sucking function. Guide wires or an inflatable balloon system or a support system can penetrate through stenosis and bending positions in occlusion conveniently. According to the catheter, the near end of a catheter body is connected with a connector, the far end of the catheter body is connected with a guide cutting device, and a guide block is arranged at the far end of the guide cutting device. The guide block is connected with the far end of the control guide wire and the far end of the cutting guide wire, the near end of the cutting guide wire is connected with the far end of the catheter body, and the near end of the control guide wire is connected with an adjusting knob used for adjusting and controlling the guide wires to make axial movement. The adjusting knob is connected to the near end of the connector. Compared with the prior art, the adjusting knob at the near end of the connector can be adjusted, thrombi at a diseased region can be cut off, a suction instrument at the Luer end can be operated, the cut thrombi can be sucked out, the guide wires or the inflatable balloon system or the support system can penetrate through the stenosis and bending positions in occlusion more conveniently.