The invention discloses a high-strength degradable bone fracture binding band and a preparation method of the high-strength degradable bone fracture binding band and belongs to the technical field of medical instruments. The bone fracture binding band is formed by combined preparation of a high-strength orientation fiber band and a randomly arranged fiber film or a random orientation thin film. The degree of crystallinity is increased through a nucleating agent, and the orientation technology is adopted to obtain the high-strength orientation fiber band; the bone fracture binding band is prepared under the condition that the linear speed of a disc-shaped yarn take-up device is greater than or equal to 500 m/min by the adoption of the solution electrospinning technology; the mass percent of a spinning solution is that a degradable polymer accounts for 5-12%, the nucleating agent accounts for 0.5-2%, and a solvent accounts for 86-95%. The orientation fiber band is arranged in a single orientation or double orientations, the random fiber film is sprayed on the surface of the orientation fiber band, or the random orientation thin film is stacked on the orientation fiber band, and then the bone fracture binding band is prepared by means of ultrasonic welding. The tensile strength and tensile modulus of the prepared bone fracture binding band are improved substantially compared with those of a randomly arranged electrostatic spinning film, and the bone fracture binding band has good application prospect with respect to repair and fixation of clinical bone fractures.