The invention provides a three-dimensional plant station simulation system based on a power grid accident. The three-dimensional plant station simulation system comprises a three-dimensional plant station simulation module and a GIS geographic information module. A three-dimensional image of a plant station is visually checked through the three-dimensional plant station simulation module. Device operation is conducted through the three-dimensional plant station simulation module. Operation information is directly transmitted to a device through a network. The device correctly responds to the operation information. Circuits with the voltage being 220KV or above and positions of transformer substations in the whole area are displayed through the GIS geographic information module so that a complete net rack graph can be formed. An alarm can be given for the fault position, and a regulating and control person can be notified to check the fault position through a flickering mode and makes a response in time. The visual and accurate foundation is provided for the regulating and control person through the system for accident analyzing and processing. Accident information is collected in real time and analyzed, the specific occurrence position of the accident is determined through the combination with mass data in an emergency command system, and the accident is related to the three-dimensional plant station simulation system and a geographic information system (GIS) according to the type of the accident.