The utility model relates to an automatic vacuumizing device of a precision numerical control two-way hydraulic press. The device is characterized by comprising a compaction cylinder fixedly connected with a press sliding bock, wherein the other end of the compaction cylinder is connected with a vacuumizing plate, and the vacuumizing plate is communicated with a vacuumizing pump station through a vacuum pipeline. The device has the advantages that automatic vacuumizing can be realized when an explosive column is extruded to different heights, the vacuum degree of a workpiece in a closed cavity of a mold can be ensured, bubbles produced in the pressing process of the explosive column can be reduced, the quality of the explosive column product is improved, and the working efficiency can also be improved.