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CN104144945A 结合铜绿假单胞菌PCRV的单可变结构域抗体 无效 - 撤回

结合铜绿假单胞菌PCRV的单可变结构域抗体
Abstract:
本发明提供能够显著抑制和/或中和铜绿假单胞菌(P aeruginosa)的多肽。所述多肽包含两种以上针对铜绿假单胞菌的PcrV蛋白的免疫球蛋白单可变结构域，其中“第一”免疫球蛋白单可变结构域和“第二”免疫球蛋白单可变结构域具有不同的互补位。
Abstract(English):

Polypeptides are provided that are capable of significantly inhibiting and/or neutralizing P aeruginosa. The polypeptides comprise two or more immunoglobulin single variable domains that are directed against the PcrV protein of P. aeruginosa, wherein the 'first' immunoglobulin single variable domain and the "second" immunoglobulin single variable domain have different paratopes.

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