The invention relates to a yellow rice wine rich in chrome, manganese, zinc, selenium and molybdenum and capable of reducing three highs. The yellow rice wine comprises the following raw materials in parts by weight: 1000 parts of yellow rice wine, 100 parts of momordica grosvenori, 30 parts of chromium manganese-enriched chrysanthemum, 20 parts of selenium molybdenum-enriched pollen pini and 5 parts of zinc gluconate; the preparation method includes the following steps: wild momordica grosvenori and chromium manganese-enriched chrysanthemum are firstly washed and dried and selenium molybdenum-enriched pollen pini is subjected to superfine grinding at a low temperature, and the three materials are then sterilized to be added into and immersed in the yellow rice wine according to the proportion. The yellow rice wine provided by the invention has a good taste and an excellent effect on reducing three highs.