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CN104195114A 一种禽肺病毒及其应用 无效 - 驳回

一种禽肺病毒及其应用
摘要：
本发明的目的在于提供一种禽肺病毒，为SHS/B株，已于2014年3月24日保藏于北京市朝阳区北辰西路1号院3号的中国科学院微生物研究所中国微生物菌种保藏管理委员会普通微生物中心，保藏编号为CGMCC No.9001。本发明的禽肺病毒用于制备疫苗。本发明筛选的禽肺病毒具有安全性好，且免疫原性高的特点，用禽肺病毒SHS/B株接种Vero细胞，收获细胞毒液，经甲醛溶液灭活后，加油佐剂混合乳化制成疫苗。能提高SPF鸡的抗体，预防禽肺病毒引起的肿头、产蛋率下降等症状，此疫苗具有高效、安全性好的优点。
摘要（英）：

The invention aims at providing avian pneumovirus which is an SHS/B strain, wherein the strain is already preserved in CGMCC (China General Microbiological Culture Collection Center) of Institute of Microbiology of CAS (Chinese Academy of Sciences) (address: 3#, Yard 1, West Beichen Road, Chaoyang District, Beijing) on March 24, 2014, with the preservation number of CGMCC No.9001. The avian pneumovirus provided by the invention is used for preparing vaccines. The screened avian pneumovirus has the characteristics of good safety and high immunogenicity. A Vero cell is inoculated by the SHS/B strain of avian pneumovirus to obtain a cell venom, the cell venom is deactivated by a formaldehyde solution, and then an oil adjuvant is added to mix and emulsify to obtain the vaccine. The vaccine can be used for improving the antibody of SPF chicken and preventing symptoms such as head swelling, decline of laying rate and the like induced by avian pneumovirus. The vaccine has the advantages of high efficiency and good safety.

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