The invention discloses a B/S based remote transformer substation monitoring system and method. A data analysis module communicates with a transformer substation monitoring master station, acquires data of the transformer substation monitoring master station and then judges, analyzes and classifies the data prior to storing the data into a database; besides, the data analysis module is provided with a mobile terminal interface which is capable of acquiring data and events actively through a corresponding IP (internet protocol) and port; when receiving SOE (sequence of event) alarm events of a transformer substation, the data analysis module gives out a voice alarm, sends an alarm short message to a specific technicist and pushes alarm to a mobile APP (application). A Web server is deployed on the database, and users can log in the Web server through domain names or the IPs remotely to view telemetering and remote signaling data and real-time and historical data of the SOE events and know operating conditions of the transformer substation anytime. High-level users can execute remote camera monitoring and remote control as well as remotely manage operation of the transformer substation.