The invention provides a double-layer hollow sound insulation concrete slab and a construction method thereof, relates to the technical field of concrete members and aims at solving the problem of degradation of sound insulation and noise reduction performance of a double-layer hollow floor slab due to the fact that some templates are enclosed in and cannot be removed out of an air layer of an existing double-layer hollow floor slab. The double-layer hollow sound insulation concrete slab comprises two parallel and spaced base plates, at least two beams spaced between the two base plates, and a prefabricated panel which is arranged at one end of each of the beams, overlapped between the adjacent two beams and made with the adjacent base plate into a whole. The construction method includes the steps of 1 manufacturing a prefabricated panel; 2 pouring the base plate at a lower layer and the beams; 3 removing templates of the base plate at a lower layer and the beams, overlapping the prefabricated panel between the adjacent two beams, and closing a cavity between the adjacent two beams; 4 pouring concrete to the prefabricated panel as a bottom mold of the base plate at a higher layer to obtain the double-layer hollow sound insulation concrete slab.