The invention discloses a network interface card state monitoring and address switching method of a region-county integrated network architecture. County scheduling node send ICMP messages to local switches and receive ICMP response messages, and all nodes can accurately determine the network interface card states of local nodes and switching the communication addresses of the nodes according to the network interface card states so as to realize redundancy mutual backup of networks; and at the same time, through sending the ICMP messages to region scheduling (specific) switches and receiving the ICMP response messages, the county scheduling nodes can determine the connection states of the local nodes with region scheduling nodes and switching the communication addresses of the local nodes according to the connection states so as to ensure that system nodes can still communicate with each other normally even if only one link works normally between the region scheduling nodes and the county scheduling nodes, and realize the network redundancy mutual backup on the region-county integrated system network architecture. Therefore, the method provided by the invention has good application prospect.