The invention relates to a traditional Chinese medicine composition for treating tongue cancer and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following Chinese herb raw materials by weight: 5-10g of berberis thunbergii, 5-10g of asiatic pennywort herb, 3-9g of Indian strawberry root, 5-15g of radix scrophulariae, 5-10g of clausena lansium, 5-10g of kumquat kernel, 3-6g of melastoma dode candrum lour root, 3-8g of lichen of parmelia saxitilis, 5-9g of lalang grass rhizome and 5-10g of Chinese fevervine herb. The traditional Chinese medicine composition can be prepared into pills, capsules and a decoction. The berberis thunbergii, the asiatic pennywort herb, the Indian strawberry root and the radix scrophulariae are capable of clearing internal heat and detoxifying; the clausena lansium and the kumquat kernel are capable of dissipating stasis and stopping pain; the melastoma dode candrum lour root, the lichen of parmelia saxitilis, the lalang grass rhizome and the Chinese fevervine herb are capable of enriching blood and tonifying qi; the various medicinal materials are combined to have an exact curative effect on the tongue cancer without toxic or side effects; the traditional Chinese medicine composition is also effective for oral cancers such as gingiva cancer, oropharyngeal cancer and lip cancer.