The invention discloses a control method and a control system for lighting equipment in a relay protection machine room. The control method comprises the following steps: step S1, performing audio recognition and character recognition on voice in a preset frequency section acquired in the machine room in advance; step S3, comparing a recognized audio with an audio and letters prestored; step S5, activating the lighting equipment so as to enable the same in a safety mode under the condition that the comparison results are consistent; and step S7, starting the lighting equipment by at least a RFID (Radio Frequency Identification Devices) technology when the lighting equipment is in a safe mode. The safety of the machine room can be improved in a lighting aspect by recognizing all aspects of the audio to enable the lighting equipment to be in the safety mode before the lighting equipment is started, and then the lighting equipment can be started by the RFID technology to prevent equipment in the machine room from operating to cause the lighting equipment started by indoor equipment started without the demand.