The invention discloses a packing method of a pressure swing adsorption tower. The adsorption tower is provided with a leakproof zone, an adsorption zone and a protection zone from bottom to top successively; the leakproof zone is provided with a leakproof silk screen, wherein the leakproof zone is packed with a leakproof agent, and the leakproof agent is columnar alumina; the leakproof silk screen comprises a fixed silk screen and a floating silk screen, and the floating silk screen is positioned above the fixed silk screen and is contacted with the leakproof agent. The method can improve the corrosion resistance of the tower bottom leakproof silk screen, effectively reduces the possibility of damage of the leakproof silk screen at the adsorption tower bottom, and ensures the long-period operation of the adsorption tower.