The invention provides a large-capacity nail tip storage box which comprises a box cover and a box body. The box cover is connected with one side of the box body in an axial moving manner. The opposite sides of the box cover are fixedly clamped. The edge of the box cover and the edge of the box body are identical in shape and size, so that a tight cavity is formed after the box cover is fastened to the box body. A first partition retaining plate and second partition retaining plates are disposed in the box body. The first partition retaining plate are vertical to the second partition relating plates. Each second partition retaining plate is a right trapezoid, the upper bottom of the right trapezoid is in contact with the edge of the box body, the lower bottom of the right trapezoid is in contact with the first partition retaining plate, and the height of the first partition retaining plate is identical with the length of the lower bottom. The box cover is of a structure with a protruding middle portion, and the protruding portion is adaptive to the position of the first partition retaining plate. The large-capacity nail tip storage box has the advantages that more nail tips can be stored, high space utilization rate is achieved, folding marks in the middle of the nail tips cannot be extruded easily, and the storage box is simple and convenient to use and high in market competitiveness.