The invention relates to a cultured fish type anti-stress domestication method and a device based on the method, and belongs to the technical field of pond culture. According to the cultured fish type anti-stress domestication method, an overwater automatic traveling device is used for dragging a fishing net with meshes of being larger than fish bodies and having a rigid framework to move back and forth in water of culture pond, so that cultured fishes in the pond gradually adapt to net dragging operation, and the loss caused by scare of the fishes during fishing and dragging is reduced. The device based on the cultured fish type anti-stress domestication method comprises a rectangular frame defined by a horizontal floating rod (7), a sinking rod (9) and a pair of vertical fixing rods (10), wherein a large-mesh net sheet (8) is fixedly arranged in the rectangular frame; the fixing rods (10) are fixedly connected with a horizontal connecting rod (6); the connecting rod (6) is fixedly connected with a floating pontoon (1); the floating pontoon (1) is provided with a solar panel (2), an accumulator (3), a controller (4) and a propeller (5); the rotation direction of the propeller is switchable.