The invention relates to a system and method for achieving real-time transmission of transformer substation device information based on shared memory. The system comprises a transformer substation device data collection module, a shared memory module and a master station management module, wherein the transformer substation device data collection module is used for collecting data information of devices inside a transformer substation and sending data changing messages to the master station management module when the data information of the devices changes, the shared memory module is used for storing the data information, collected by the transformer substation device data collection module, of the devices in a classified mode according to plant station serial numbers, and the master station management module is used for reading the data information, stored in the shared memory module, of the corresponding positions according to the plant station serial numbers and the positions of data blocks in the data changing messages. According to the system and method for achieving real-time transmission of the transformer substation device information based on shared memory, the substation device operation quantities can be efficiently organized and integrated, the information can be rapidly obtained and integrally transmitted, monitoring real-time performance, transmission reliability and collection efficiency are improved, and the system and method have the wider application range.