The invention relates to a method for preventing and treating brown rot of peaches. The method comprises the following steps: soaking peaches in hypotaurine solution at the concentration of 5-20 ppm for 0.5-2 h, processing and storing. The rot rate and the plaque diameter of peaches which have been soaked in the hypotaurine solution are obviously reduced, the activities of relative protective enzymes (phenylalanine ammonia-lyase and chitinase) are obviously increased, and brown rot of peaches is obviously suppressed. The method is safe and efficient, the process is simple, the method can be widely applied in storage of harvested peaches, and thus the method has broad market prospect.