The invention discloses a substation engineering project three-dimensional calculation quantity model generation system and method. The method comprises a station region management module for establishing a substation engineering project three-dimensional calculation quantity model file, dividing substation engineering into unit projects by utilizing project division, dividing each unit project into professional projects by utilizing professional division, and integrating three-dimensional calculation quantity models in all professional projects to a station region total model through a cooperation module; a modeling module for providing an interactive modeling mechanism, and constructing and displaying the three-dimensional calculation quantity model through a CAD modeling method or a drawing modeling method; and a model module for packaging common model objects and used for storing model data and constructing a geometric model. The generation system and method adopt project division as a general principle, the station region total model as total display, and three professions as module utilization, so that project directory is clear, utilization flow is clear, and visualization degree is improved greatly.