The invention discloses an anti-seepage plastic pipe structure which comprises an inner pipe body and an outer pipe body. The inner pipe body is located in the center in the outer pipe body. A sealing cavity is formed between the inner pipe body and the outer pipe body and is filled with sealants. Multiple protruding blocks protruding outwards are evenly distributed on the outer surface of the inner pipe body and are embedded in the sealants. At least one through hole communicated with the sealing cavity is formed in the outer pipe body. The outer surface of the outer pipe body is further wrapped by a skid resistant layer. A steel wire mesh is arranged in the sealing cavity around the inner pipe body and is embedded into the sealants. According to the anti-seepage plastic pipe structure, the sealing cavity is arranged between the inner pipe body and the outer pipe body, glue injection sealing can be carried out in site on a plastic pipe, pipeline internal seepage caused by shrinkage or stress change of the sealants during long-term use of the plastic pipe is avoided, when seepage occurs, replacement of a new plastic pipe is not needed, on site repair can be directly carried out, and construction cost is reduced greatly.