The invention discloses a health report intelligent prompt system and method based on O2O health management. The health report intelligent prompt system comprises detection equipment and a health management platform. The detection equipment comprises a sign information detection module, a voice prompt module and a voice broadcasting module. The sign information detection module is used for collecting sign information of a patient and sending the sign information to the health management platform; the health management platform generates a health report according to the sign information and sends prompt information of the health report to the voice prompt module within a preset time period, and the voice prompt module prompts the patient to read the health report; the voice broadcasting module performs voice broadcasting on the prompt information of the health report to effectively prompt, supervise and urge the patient to check the health report in time, and the current physical condition and the execution condition of the health report of the patient can be known.