The invention relates to a surface-oleophobic aluminum plastic film for packaging a lithium battery. The surface-oleophobic aluminum plastic film comprises a CPP layer (1), an inner bonding layer (2), an aluminum foil layer (3), an outer bonding layer (4), a nylon layer (5) and an oleophobic protective layer (6) which are sequentially arranged from inside to outside, wherein the oleophobic protective layer (6) comprises a fluorine-modified coating, a silicon-modified coating or a fluorine and silicon co-modified coating. The invention also provides a preparation process of the surface-oleophobic aluminum plastic film for packaging the lithium battery. When the aluminum plastic film is in contact with accidentally-dropping electrolyte in the process of packaging and injecting the electrolyte, the aluminum plastic film cannot be corroded, and the slippery property of the outer surface of the film is improved.