The invention relates to a receiving and sending circuit of a configurable PCI bus based on the FPGA technology. The circuit comprises an FPGA device, a PCI top-layer module is arranged in the FPGA device and comprises an instantiated ALTERA PCI IP core, a rear-end matching circuit, a peripheral circuit control module and a storage circuit control module, and all the modules are packaged into a whole through the PCI top-layer module. The function of a dedicated chip is transferred into the FPGA device, the area of a board card is saved, and cost is lowered. High transportability is achieved, the device and a pin can be modified according to the actual needs of the board card, and a peripheral circuit and a memorizer can be expanded conveniently. The receiving and sending circuit is achieved through a programmable logic device, and is simple in structure, fast in operation and high in reliability.