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发明公开
CN104490906A 甘草酸在制备预防和治疗电离辐射损伤药物方面的应用 无效 - 撤回

甘草酸在制备预防和治疗电离辐射损伤药物方面的应用
摘要：
本发明涉及医药领域，公开了甘草酸在制备预防和治疗电离辐射损伤药物方面的应用。甘草酸，亦称甘草皂甙、甘草甜素，是从中药甘草中分离的一种皂甙成分，英文名称Glycyrrhizin，Glycyrrhizic acid，分子式C12H22O16，分子量833.94，CAS号1405-86-3，本发明公开了甘草酸在细胞水平和动物活体水平发挥辐射保护作用，并且在致死剂量、亚致死剂量以及低剂量辐射的广泛剂量范围下，均有保护作用，甘草酸质量稳定，成本低廉，来源广泛，可用于制备预防和治疗电离辐射造成的相关损伤救治和疾病治疗方面的药物。
摘要（英）：

The invention relates to the field of medicines and discloses application of glycyrrhizinic acid in preparation of a medicine used for preventing and treating ionizing radiation injury. Glycyrrhizinic acid is also called glycyrrhizin and is a saponin ingredient separated from traditional Chinese medicine liquorice with English names of glycyrrhizin and glycyrrhizic acid and a molecular formula of C12H22O16 and molecular weight of 833.94 and CAS number of 1405-86-3. The invention discloses a radiation protective effect of glycyrrhizinic acid in cell level and living animal, glycyrrhizinic acid has the protective effect in a wide-dosage range including lethal dosage, sub-lethal dosage and low-dosage radiation, quality of glycyrrhizinic is stable, cost is low, source is wide, and glycyrrhizinic can be used for preparing a medicine used for preventing and treating related severe injuries and diseases which are caused by the ionic radiation.

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