The invention relates to the field of oil-gas field exploration and development, in particular to a fractured reservoir permeability tensor and anisotropy quantitative prediction method. On the basis of stress field numerical simulation, a static coordinate system and a dynamic coordinate system are integrated into a geodetic coordinate system by using the current occurrence of fractures, multiple groups of fracture permeability tensor quantitative prediction models are established, quantitative calculation formulas of the permeability principal direction and data are given, and the permeability of fractures in units in different directions is predicted by adjusting the rotation angle of the dynamic coordinate system. The fractured reservoir permeability tensor and anisotropy quantitative prediction method is based on strict mathematical algorithm derivation, a corresponding calculating program can be developed by using computer programming languages, fractured reservoir permeability tensor and anisotropy quantitative prediction is realized, the prediction cost is low, the operability is high, and the prediction result has certain guiding significance on determining the fault block permeability dominant direction, deploying and developing well patterns reasonably, and determining the spatial location relationship between an injection well and a producing well.