The invention relates to the field of power grid safe operation technologies, in particular to an intelligent fault-analysis-prevention system and a working method of the intelligent fault-analysis-prevention system. The problem that in the prior art, a selector switch is inaccurate in switching in the field of electric fault-locking-prevention technologies is solved. Through establishing the intelligent fault-analysis-prevention system composed of an interface adaptation module, a data processing module, a database server, a monitoring server, a network topology analysis module and a fault-analysis-prevention control module, current equipment operation information of a power grid and power grid users is collected in real time, locking information of all substation equipment is obtained, a final judgment result is generated through comparison and analysis of the locking information and data stored in the database server, and fed back to the substation equipment for execution, and therefore the technical problem that in the field of electric fault-locking-prevention technologies, the selector switch is inaccurate in switching is solved.