The invention discloses a comprehensive ruminal tympany treatment device, belonging to the technical field of medical apparatuses and instruments for veterinary medicines. A puncture deflation needle comprises a deflation part and a medicine injection part, medicines with effects of stopping fermentation and helping digestion or strengthening the heart and invigorating stomach can be filled into the rumen, and deflation is performed simultaneously. In addition, the medicine injection part can be developed in the ruminant's rumen, rotary medicine injection is realized, mechanical beat defoaming is performed, and the condition that the vent holes are blocked by bubble chime is avoided. Meanwhile, the filled medicines can be subjected to multi-point, wide-range and all-around application in the rumen, so that the deflating, defoaming and medicine filling effects are greatly improved. Moreover, the rotating speed of the medicine injection part can be manually controlled, rapid rotation can be performed at first, the operation of mechanically crushing the air bubbles in the rumen is taken as the main aim, the rotating speed is reduced, the drug is delivered to the rumen during medicine spraying and bubble crushing, the air pressure in the rumen and the heart conditions of diseased animals can be monitored in real time during operation, and intra-operative complications are avoided.