The invention relates to a construction method of a public health emergent event domain knowledge base. The method comprises the following steps: analyzing each domain involved by a public health emergent event life cycle, and searching a related document to obtain a corpus; constructing an event frame by extracting attribute information in a sentence; processing text information to form a standard information markup system; taking the obtained attribute information as a seed attribute, designing a seed mode, and selecting new matching related information depending on the seed information to obtain more attribute information; constructing a public health emergent event domain body by using the attribute information. The public health emergent event domain knowledge base constructed by the construction method of the domain knowledge base is more accurate and complete, simple and efficient, a new emergency plan is favorably generated and executed, a standard reference is provided for emergency treatment of emergent events, the emergency treatment efficiency can also be improved, and a reference is provided for next scientific research.