The invention relates to a synergistic compound composition containing two active components, belonging to the field of pesticides. The composition comprises an active component A and an active component B, wherein the component A is pyriminostrobin, the component B is one selected from the group consisting of nicotine type or insect growth regulator type insecticidal and acaricidal agents, and a weight ratio of the component A to the component B is 1:99 to 99:1. The structure of pyriminostrobin is described in the specification. The composition provided by the invention has obvious synergistic effect and can be used for prevention and treatment of a plurality of insects and mites.