In a distillation apparatus including a plurality of distillation columns, total energy consumption is reduced while controlling a cost increase. Provided is a distillation apparatus including a first distillation column and one or more second distillation columns, wherein the first distillation column includes: a higher-pressure part including the whole or a part of a rectifying section and configured to perform gas-liquid contact at a relatively high pressure; a lower-pressure part including the whole or a part of a stripping section and configured to perform gas-liquid contact at a relatively low pressure; a vapor line, including a pressurizing means, for directing a vapor discharged from a column top of the lower-pressure part to a column bottom of the higher-pressure part; and a liquid line for directing a liquid discharged from the column bottom of the higher-pressure part to the column top of the lower-pressure part, and the distillation apparatus includes: a first heat exchange structure configured to transfer heat from the rectifying section of the first distillation column to at least one of the one or more second distillation columns by heat exchange; and a second heat exchange structure configured to transfer heat from at least one of the one or more second distillation columns to the stripping section of the first distillation column by heat exchange.