The invention discloses a MAX 262 and FPGA based squeak detection suppression system. The system comprises a squeak detection circuit, a squeak suppression circuit and a relay switching circuit. The squeak detection circuit comprises a frequency detection portion and an amplitude detection portion. The frequency detection portion monitors sound signal frequencies in real time, the amplitude detection portion is used for detecting the sound amplitude, and the squeak suppression circuit destroys produced amplitude conditions and phase conditions. By the aid of the system and the method, compared with the traditional manual squeak detection and suppression method, the system and the method have the advantages of being full-automatic, short in delay, small in size and the like.