The invention relates to an evaluation system and method for a vital sign monitoring device. The evaluation system comprises a control module, a vital sign signal source simulation module, a vital sign signal regulation circuit module and a display module. The method for evaluating the device to be evaluated through the evaluation system includes the steps of setting initial parameters of the evaluation system, measuring gain calibration parameters of the evaluation system, evaluating the device to be evaluated, and displaying the evaluation result on the display. By means of the evaluation system and method, vital sign signals of different types can be provided for the device to be evaluated, and various characteristics such as the transfer function, the frequency response, the in-band amplitude fluctuation, the signal-to-noise ratio and focus characteristic signals of the device to be evaluated are evaluated. The problem that by means of an existing vital sign monitoring device, in the research and development process, the effectiveness of a model can not be verified through theoretical calculation modeling and analog simulation.