The invention provides a dynamic description method of medium-high-permeability sandstone reservoir water flooding sweep efficiency and water flooding pore volumes. The method includes: building a planar and longitudinal sweep efficiency prediction model and plate aiming at the sweep efficiency researches of a medium-high-permeability sandstone reservoir; building a planar and longitudinal water flooding pore volume models and plates of different areas aiming at the water flooding pore volume researches of the medium-high-permeability sandstone reservoir. The description method has the advantages that the method is high in practicality, the sweep efficiency and water flooding pore volume change features of different parts of homogeneous and non-homogeneous models are dynamically reflected, and theoretical basis is provided to the future residual oil potential seeking of water flooding reservoirs.