The invention discloses a method and a device for processing the parameter restriction and mutual exclusion of human-computer interaction interface software, and is used for realizing a purpose that the processing logic of the parameter restriction and mutual exclusion of each assembly is independent out of software business development logic so as to realize the effective management of the parameter restriction and mutual exclusion. The method has the main thoughts that each assembly and the description information of each assembly are stored in a file of a preset format; for the parameter restriction of the assembly, the description information at least comprises an assembly name, an assembly type and a parameter restriction condition; for the parameter mutual exclusion of the assembly, the description information comprises the assembly name, the assembly type, a current parameter value, a parameter mutual exclusion relationship and a mutual exclusion solution; the file of the preset format is analyzed to store the assembly and the description information of the assembly to a cache; when the parameter of the assembly changes, the cache is looked up to obtain the description information of the assembly; and according to a parameter restriction condition or the parameter mutual exclusion relationship in the description information, parameter restriction or mutual exclusion processing is carried out.