An interactive amusement system, interactive wearing system and a data transmission circuit for biological contact are provided in the present invention. The interactive wearing system includes a first wearing device and a second wearing device. The first and the second wearing devices are includes a contact conductor for respectively contacting with the users. When a first user wears the first wearing device and a second user wears the second wearing device, and the first user touches the second user, a secret message that has been set into the first wearing device by the first user is transmitted to the second wearing device. Therefore, interactivity between toys and people and among people is improved.