The invention discloses a manufacture method of conductive fire-retardant acrylic fiber. The manufacture method comprises the following steps: (1) preparing a spinning solution; (2) performing spinning formation; (3) performing copper salt treatment; (4) adding acrylic fiber containing copper ions obtained in the step (3) into a mixed aqueous solution, and reacting in an airtight high-temperature reaction kettle at 120-140 DEG C for 4-5 hours to prepare the fire-retardant acrylic fiber; (5) taking out and cleaning the acrylic fiber obtained in the step (4), and putting the acrylic fiber at 70-90 DEG C for 2-3 hours in a constant-temperature manner. Through the manner and with the adoption of the manufacture method of conductive fire-retardant acrylic fiber, the acrylic fiber subjected to the antistatic treatment can prevent static electricity during application, ensures normal application of a user, has a fire-retardant function, and overcomes the flammable defect of cloth.