The invention provides a multi-level settlement coordination control method applicable to centralized deployment. The multi-level settlement coordination control method comprises the following steps: dividing business scenes, and establishing a cross-scene business data sharing strategy based on scene copying; establishing a cross-scene settlement process; creating a process instance, and driving the process to run through business operation; carrying out centralized management and control on process indexes and business indexes. The method provided by the invention is used for realizing business data interaction and process turnover among different scenes through business scene division, the scene sharing strategy, a cross-scene process definition, centralized monitoring and control of indexes and the like; the efficiency of the settlement work is greatly improved; technical conditions are provided for changing monthly settlement into weekly settlement for a purpose of adapting to the current market and the real-time market in future.