The invention provides a cold fusion reaction device which serves as the reaction device of atomized liquid fuel. The cold fusion reaction device comprises a heat conduction layer and an electrode, wherein the heat conduction layer is the shell of the reaction device, and the electrode penetrates the inner cavity of the reaction device. The cold fusion reaction device has the advantages that high-frequency currents are guided in through the electrode to generate electromagnetic fields so as to stimulate the deuterium atoms in the atomized liquid fuel fed into the reaction device to perform fusion reaction under normal temperature to release huge energy, and the energy is transmitted out through the heat conduction layer; by the stacked and varied electromagnetic fields, the liquid fuel can perform cold fusion reaction under normal temperature; the liquid fuel extracted from sea water releases huge energy through cold fusion reaction in the special reaction device and under special reaction conditions.