The invention discloses a method, device and system for generating transformer station load transfer control parameters. The method for generating the transformer station load transfer control parameters comprises the following steps: according to state change of an electric power system network, adjusting elements in a basic scale matrix, wherein the basic scale matrix is constructed based on the topology structure of the electric power system network, the elements in the basic scale matrix indicating switch information and risk values of paths among nodes in the electric power system network, and the switch information indicating a switch frequency needed for connection two nodes in the electric power system network; and executing operation on the adjusted basic scale matrix so as to generate the switch information and the risk values of the paths used for transformer station load transfer control as the transformer station load transfer control parameters. The method, device and system provided by the invention can simplify the calculation complexity. Besides, the invention can provide more comprehensive information about various transfer schemes.