The invention discloses an automatic screwing device for a perfume bottle. The automatic screwing device comprises a stander, wherein an operating bedplate is horizontally installed on the stander, the operating bedplate is provided with a control box, a rotating disc which is driven by a motor to rotate is installed in the middle of the operating bedplate, a plurality of racks are uniformly installed on the rotating disc, the operating bedplate is sequentially provided with a bottle feeding machine, a sieve vibrating disc, a pipe insertion machine, a transparent cover vibrating disc and a good product discharging opening along the clockwise direction, a sieve detection device is installed between the sieve vibrating disc and the pipe insertion machine by virtue of an installation support, a sieve screwing device is installed between the pipe insertion machine and the transparent cover vibrating disc by virtue of the installation support, and a transparent cover detection press-in device is installed between the transparent cover vibrating disc and the good product discharging opening; a sieve position adjusting device is installed between the pipe insertion machine and the sieve screwing device by virtue of the installation support. The automatic screwing device has the beneficial effects that the practicability is realized, the production cost is low, the use is convenient, the production efficiency for assembling the perfume bottle can be improved, and the labor intensity can be alleviated.