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发明公开
CN104837797A 制备氟化醇的方法 无效 - 撤回

制备氟化醇的方法
摘要：
本发明涉及一种制备式(I)的氟化醇：RfCH2CH2OH(I)的方法，通过在引发剂和碱存在下，使氟化碘化物与烷基乙烯基醚接触以生成中间体半缩醛或醛或它们的混合物，之后使式(II)的半缩醛：RfCH2CH(OCxH2x+1)m(OH)p(II)或式(III)的醛：RfCH2CHO(III)或它们的混合物氢化来获得式(I)的化合物。
摘要（英）：

The present invention is directed to a process for preparation of fluorinated alcohols of Formula (I): RfCH2CH2OH (I) by contacting a fluorinated iodide with an alkyl vinyl ether in the presence of an initiator and a base to generate an intermediate hemi-acetal or aldehyde or a mixture thereof, followed by hydrogenation of the hemi-acetal of Formula (II): RfCH2CH(OCxH2x+1)m(OH)p (II) or aldehyde of Formula (III): RfCH2CHO (III) or a mixture thereof, to yield a compound of Formula (I).

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