The invention discloses compost for the industrialized production of coprinus comatus. The compost comprises the following components in percentage by weight: 50-70% of biogas residue, 5-40% of corncob, 13% of bran, 5% of corn flour and 2% of gypsum. By using the compost provided by the invention for cultivating the coprinus comatus, the raw material costs for production of the coprinus comatus is reduced, the production cycle can be shortened, the yield can be improved, the energy consumption can be reduced, the biogas residue, the residue of large-scale methane fermentation can be recycle, and the circular chain of biomass energy can be prolonged.