The invention relates to a multimedia advertisement system which comprises a suspension part and an advertisement assembly. The advertisement assembly is connected with the suspension part, and comprises a plurality of advertisement boxes and connecting assemblies. The advertisement boxes are connected in series through the connecting assemblies and arranged at intervals. Each connecting assembly comprises a tie rope, an optical fiber and a power line, wherein the tie rope is connected with the suspension part. The multimedia advertisement system further comprises a sleeve, wherein the connecting assemblies are arranged in the sleeve. According to the multimedia advertisement system, the different advertisement boxes can display advertisements in a distinguishing mode according to different positions after being connected in series, and the advertisement display is higher in targeted performance; meanwhile, the multimedia play content can be controlled in a concentrated mode, the traditional display mode of plane LEDs or suspended advertisement banners is changed, and the building space can be fully utilized.