The invention provides a process method for preparing a super-amphiphobic zinc surface. According to the process method, electrochemical etching and low-surface-energy material modification are combined; a metal zinc plate is cleaned by virtue of an organic solvent to remove oil and is mechanically polished to remove a surface oxide layer, the cleaned zinc plate is fixed on a positive electrode clamp to serve as a positive electrode, and a graphite plate with same area size with the zinc plate is fixed on a negative electrode clamp to serve as a negative electrode; a used electrochemical etching solution is a neutral salt solution with a proper concentration, constant current is introduced into two ends of the positive electrode and the negative electrode, and by controlling the machining time and machining current in the electrochemical etching process, a proper binary micro-nano coarse structure is machined on the surface of the zinc plate; after the binary micro-nano coarse structure produced by virtue of electrochemical etching is modified by virtue of the low-surface-energy material, the super-amphiphobic zinc surface can be obtained. The process method has the advantages of simplicity in operation, high efficiency, good environmental friendliness, low cost and the like and is expected to be applied to large-scale industrial production.