The invention relates to a method and a device for determining configuration parameters of a radiofrequency identifier reader. The method includes: in response to an application requirement profile input according to a profile template, according to a profile parameter in the application requirement profile, calculating an expected key parameter index which is a parameter index necessary for determining configuration parameters of the radiofrequency identifier reader; according to the calculated expected key parameter index, with reference to a database which records a correspondence between the key parameter index and configuration parameters of the radiofrequency identifier reader, determining the configuration parameters of the radiofrequency identifier reader. The method and the device according to the embodiment have the advantages that the radiofrequency identifier reader can be more efficiently configured.