The invention relates to a high-pressure water-mist venturi pipe assembly which can effectively solve the problem about cooling and dust removing in a dusty gas discharging process. The technical scheme is that the high-pressure water-mist venturi pipe assembly comprises a water tank, a high-pressure pump and a venturi pipe, wherein a water outlet of the water tank is connected with a water inlet of the high-pressure pump; a stainless steel pipe is mounted at a water outlet of the high-pressure pump; an outlet end of the stainless steel pipe extends into a straight pipe section of the venturi pipe, the diameter of the straight pipe section is smaller, and a high-pressure water-mist nozzle is mounted at the extending end part. The high-pressure water-mist venturi pipe assembly is novel and unique in structure, simple, reasonable, easy to produce, low in cost and low in water consumption, flue gas and water mist are combined to form large-particle fog drips falling down, the whole pipe can be the dust falling area, accordingly, the space resource is sufficiently utilized, the pipe is remarkably shortened, the cooling and dust removing effects are good, the use is convenient, and good social and economic benefits are achieved.