A wide area measurement system adaptive time-delay compensation method relates to a time-delay compensation method. At present, for methods adopting prediction compensation, the duration of prediction time is directly set at a fixed value according to experience, the adaptation is poor, and the prediction compensation error is large. The method provided by the invention comprises the following steps of determining the time-delay duration of prediction compensation required by each PMU substation of a wire area measurement system; selecting a corresponding measurement signal according to needs, performing prediction compensation, performing pretreatment of the measurement signal, wherein the pretreatment comprises detection and processing of abnormal data in historical data, detecting whether abnormal data occur by calculating whether the measurement signal data change rate is suddenly changed or not, and replacing the abnormal data when the abnormal data are detected; and a step of performing prediction compensation of data of the selected measurement signal. The time-delay compensation method of the technical scheme is simple and reliable, the calculation data size is small, the prediction compensation error is small, and accurate prediction compensation is achieved.