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发明授权
CN104906099B 一种氯喹与长春新碱的药物组合 有权

一种氯喹与长春新碱的药物组合
摘要：
本发明公开了一种氯喹与长春新碱的药物组合，包括氯喹、长春新碱，其中氯喹含量为2‑40μM，长春新碱含量为10nM，或者氯喹含量为5‑50μM，长春新碱含量为20nM；两种剂量的氯喹与长春新碱可协同杀伤、抑制包括视网膜母细胞瘤和肾母细胞瘤在内的多种儿童实体肿瘤，可作为化疗药物使用。本发明与常规用药量相比，用量少，毒性低；杀伤、抑制视网膜母细胞瘤和肾母细胞瘤的效果显著。
摘要（英）：

The invention discloses a pharmaceutical composition of chloroquine and vincristine. The pharmaceutical composition comprises 2-40mu M of chloroquine, 10nM of vincristine, or 5-50mu M of chloroquine and 20nM of vincristine. Chloroquine and vincristine of two dosages can synergically kill and inhibit multiple children solid tumors including retinoblastoma and nephroblastoma, and can be used as a chemotherapeutic medicine. Compared with an ordinary medicine, the pharmaceutical composition is small in dosage, low in toxicity and remarkable in effect in killing and inhibiting retinoblastoma and nephroblastoma.

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